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Description

Acute lung injury models in mice demonstrate reduced inflammatory cell infiltration, increased superoxide dismutase activity, and decreased TNF- and IL-6 production

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Experimental studies show bidirectional interactions between circadian and neuroendocrine systems, where neurotransmitter imbalances such as dopamine dysregulation impair clock function, and disruption of clock genes leads to neuroendocrine deficits (118, 119)

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